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Malaria parasite transforms itself to hide from human immune system

To evade the human immune system and enter red blood cells, a normally active gene in the malaria parasite nucleus goes into silent state—then switches back to active state when immunity wanes.

In order to spread disease inside the human body, the malaria parasite must evade the human immune system—which it does remarkably well. Now, researchers at Harvard School of Public Health (HSPH) have uncovered details about the mechanism by which the parasite, Plasmodium falciparum, avoids detection—it changes a critical protein on its surface that it uses as one of several molecular “keys” to enter into a new red blood cell…>>>more

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